"Perhaps not the friendliest kind for market participants, many of whom were hoping for a more resounding rebuke of Democrats given inflation realities."
All eyes are expected to turn to US inflation data, due later Thursday, to gauge the speed of future rate hikes by the Federal Reserve.
"US growth looks still too strong to bring inflation down," Tapas Strickland of National Australia Bank said in a note.
"The ongoing resilience in the (consumer prices) data and stickiness in inflation continue to point to the Fed hiking rates closer to 5.0 percent or higher."
Fed officials have raised their policy rate to a range of between 3.75 to 4.0 percent.
Markets in Asia were already grappling with the impact of strict zero-Covid measures in China, with supply chains and activity slowed by harsh lockdowns and testing policies.
"China's domestic demand is weak and their key trading partners are entering recession territory," said Edward Moya from Oanda.
"China is also continuing to struggle with COVID as Guangzhou has to return to mass testing."
The crypto world was also rocked by a surprise decision from Binance, the world's biggest cryptocurrency platform, to scrap a possible acquisition of rival FTX.com a day after disclosing it had signed a non-binding letter of intent to buy it.
The near-collapse of FTX has plunged bitcoin to a two-year low.
"You can't deny the growing correlation between bitcoin and risk assets," said Innes.
"The FTX news is having an outsized effect on asset prices," he said, adding that "all ships were sinking on the crypto tumult."