The plane was carrying six military personnel and also monks who were due to attend a ceremony at a Buddhist monastery, other media reports said.
There were no reports of casualties among people on the ground.
The pilot and one passenger survived and were taken to a military hospital, according to a resident and posting by a community group.
It was not immediately clear what had caused the crash.
Myanmar has long had a poor air safety record.
Photographs on social media showed a badly damaged fuselage lying its side.
Myanmar has been in turmoil since a military coup ousted the elected government led by Aung San Suu Kyi on 1 Feb., with daily protests in towns and cities and fighting in borderlands between the military and ethnic minority militias.