D614G protein found in 95pc coronavirus in Bangladesh

Scientists in Bangladesh have conducted genome sequencing of 222 coronaviruses as of 16 July and found that ‘D614G’ protein is mostly causing the infection in the country.

The D614G protein was found active in 95 per cent of the decoded genome of the country, said BCSIR.

Among the total 222 decoded genes of coronavirus, scientists at the Bangladesh Council of Scientific and Industrial Research (BCSIR) sequenced the genome of 171.

BCSIR scientists find that the virus mutated 590 times at genomic level and 273 at protein level in Bangladesh.

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Selim Khan, the head of genomic research center at BCSIR, said out of the 1,274 proteins in the coronavirus, those numbered between 346 and 512 were found in the countries where the coronavirus wreaked havoc. But those proteins were not found in Bangladesh’s coronavirus yet.

So far, Bangladeshi scientists have submitted data from 222 coronavirus genome sequencing to the National Center for Biotechnical Information (NCBI) of the US and Global Initiative on Sharing All Influenza Data (GSAID) of Germany.

Apart from BCSIR, nine more government and private organisations are working to decode the gene of the lethal virus.

Scientists said that genomic sequencing helps to develop vaccines for the virus.

Scientists at the genomic research center said absence of protein between 346 and 512 in Bangladesh is a silver lining.

Selim Khan said it is important to sequence the gene of the coronavirus in large scale as it mutates rapidly.

BCSIR scientists are working to ensure that, he added.

Scientists at the genomic research centre started their effort to decode genome sequence of the virus on 23 May. The 20-strong team consists of nine scientists and five virologists. They revealed the gene on 26 March for the first time which was published in GSAID.

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The Scientists are collecting samples and medical history of patients around the country with the help of the National Institute of Laboratory Medicine and Referral Center.

So far, scientists around the world have completed genome sequencing of 66,855 coronavirus samples.

Selim Khan said the countries which decoded the genome sequence more have become more successful in containing the virus and proliferating the development of vaccines.

New Zealand and Australia have decoded genome sequences of 25 and 75 per cent of the virus in their respective countries and they were able to contain the spread.

Seeing Bangladesh’s effectiveness and quickness in genome sequencing, University of Nottingham in UK has agreed to fund the project, Selim Khan said, adding they are planning to decode genome sequence of one thousand more samples if the agreement with the UK university got finalized.