The drama tells the true story of Syrian sisters Yusra and Sara Mardini, who nearly drowned in the Mediterranean in 2015 as they tugged a rubber boat packed with refugees to a Greek island.
Their heroics drew international attention, and a year later, Yusra won her heat in the Rio Olympics as part of the Games' first ever refugee team.
As well as showing the Mardinis' harrowing journey, "The Swimmers" aims to put a relatable face on refugees. It portrays the sisters' carefree lives before war arrived, and their bitter bemusement at finding European tourists frolicking in the same sea they had barely survived crossing hours earlier.
"We really hope that it will change the mind of a lot of people, because a lot of people have a wrong image of refugees," Nathalie Issa, who plays Yusra, told AFP.
"I know how badly (people in the West) are seeing the refugees, I know how Arabs are seen, I know how they portray them in films," added Manal Issa, playing Sara.
Swift fan outrage
Elsewhere on Thursday was the world premiere of "The Inspection," about a young Black man who enlists in the Marine Corps after being thrown out of his mother's home for being gay.
It is one of several LGBTQ-themed movies at TIFF, along with Harry Styles' portrayal of a closeted police officer in "My Policeman," and Universal's "Bros" starring Billy Eichne, the first major LGBTQ rom-com from a top Tinseltown studio.
But the festival's first night was beset with chronic ticketing problems, with attendees unable to access digital tickets they had purchased in time to attend the opening films.
At a festival that typically stands apart from rivals by prioritizing public accessibility, fans of Taylor Swift vented their particular outrage at failing to secure tickets to a tiny panel event Friday featuring the singer and her movie "All Too Well: The Short Film."
"Literally in downtown Toronto... and I'll wake up knowing I won't see Taylor at #TIFF22 even tho it's down the street," tweeted fan @missegyptiana.
Spielberg hits Toronto
Renowned for drawing large cinephile crowds to its premieres and red carpets, the Toronto International Film Festival was hit hard by the pandemic, and is banking on a return to its full glitz and glamor after two muted years.
Steven Spielberg will lead a host of Hollywood A-listers across the border for the world premiere of his deeply personal, childhood-inspired "The Fabelmans."
Other stars due in Toronto this weekend include Jessica Chastain and Eddie Redmayne in "The Good Nurse," Jennifer Lawrence in "Causeway," Viola Davis in "The Woman King," and Nicolas Cage in "Butcher's Crossing."
Director Rian Johnson launches "Glass Onion: A Knives Out Mystery," a whodunit sequel in which Daniel Craig's sleuth meets a star-studded cast including Edward Norton, Ethan Hawke and Jada Pinkett Smith.
And in his first film since the 2018 best picture Oscar winner "Green Book," Peter Farrelly brings "The Greatest Beer Run Ever," starring Zac Efron. TIFF runs until 18 September.