This refers to reductions to their biggest source of emissions, often from the use of their products, or so-called Scope 3 emissions.
The 250 companies together account for more than a third of global emissions. Many campaigners say it is crucial for big polluters to set such interim targets so that authorities can gauge and drive global progress towards the Paris goals.
To try and accelerate action, the G7 group of wealthy nations this month backed moves to force companies to disclose their exposure to climate-related risks, raising pressure on them to put a plan in place to mitigate them.
"Without more incentives for 80 per cent of the companies in these key sectors to disclose basic plans, we are unlikely to have the information necessary for markets and regulators to act constructively," said Tim Nixon, chief executive of data research firm Signal Climate Analytics.